Biblioteca de referencias

G
ESPACIO de ablación con campo pulsado › Bloque G › G4

Guías y evidencia

Lo que recomiendan las guías y lo que demuestran los estudios, separando siempre lo aprobado de lo que se investiga.

G4

Todas las fuentes citadas en el ESPACIO, en formato Vancouver, con DOI y PMID verificados, filtrables por tema y descargables para un gestor bibliográfico.

Descargar en RIS (111 referencias)

Artículos y guías en PubMed (104)

  1. Alhede C, Heinsen LJ, Sandgaard MR, Pontoppidan J, Wade KV, Gang U, et al. A Comparison of Safety and Outcome Using Three Different Sedation Strategies During Pulsed Field Ablation for Atrial Fibrillation. J Cardiovasc Electrophysiol. 2026;37(10):2393-2402. doi:10.1111/jce.70516 · PMID 42801688D4
  2. Almorad A, Scacciavillani R, Vetta G, Lyne J, Rodriguez J, Zaher W, et al. Pulsed electric field for pulmonary vein isolation in paroxysmal atrial fibrillation: A multicenter experience comparing pentaspline and lattice-tip catheters. Heart Rhythm O2. 2026;7(8):1479-1488. doi:10.1016/j.hroo.2026.04.014 · PMID 42666876C3
  3. Almorad A, Sebag FA, Kronborg MB, Sohns C, De Potter T, Adragão P, et al. Pulsed field ablation with a variable loop circular catheter in atrial fibrillation: Acute outcomes from the VARIPURE multicenter study. Heart Rhythm. 2026;pii: S1547-5271(26)02516-6. doi: 10.1016/j.hrthm.2026.06.040. doi:10.1016/j.hrthm.2026.06.040 · PMID 42392466G3
  4. Anter E, Mansour M, Nair DG, Sharma D, Taigen TL, Neuzil P, et al. Dual-energy lattice-tip ablation system for persistent atrial fibrillation: a randomized trial. Nat Med. 2024;30(8):2303-2310. doi:10.1038/s41591-024-03022-6 · PMID 38760584G2
  5. Arana-Rueda E, Rubio-Campal JM, Campos B, Rodríguez-Entem F, Calvo D, collaborators of the Spanish catheter ablation registry. Spanish catheter ablation registry. 24th official report of the Heart Rhythm Association of the Spanish Society of Cardiology (2024). Rev Esp Cardiol (Engl Ed). 2025;78(12):1088-1099. doi:10.1016/j.rec.2025.08.009 · PMID 41076237G3
  6. Ballesteros G, Barrera A, Pérez Castellano N, Mazuelos Bellido F, Fernández-Ruz L, Bertelli G, et al. From trial to practice: early multicenter real-world experience with the circular pulsed field ablation catheter. J Interv Card Electrophysiol. 2026;doi: 10.1007/s10840-026-02410-x. doi:10.1007/s10840-026-02410-x · PMID 42536270G3
  7. Baravia PA, Alkatiri AA, Bramantyo BB, Barabanuas Nurfairudz GP, Hanafy DA, Firdaus I. Intravascular Haemolysis and Acute Kidney Injury Following Pulsed Field Ablation: A Systematic Review and Meta-Analysis. Heart Lung Circ. 2026;pii: S1443-9506(26)00401-4. doi: 10.1016/j.hlc.2026.04.117. doi:10.1016/j.hlc.2026.04.117 · PMID 42711166C4
  8. Bazan V, Arana E, Rubio-Campal JM, Calvo D, collaborators of the Spanish catheter ablation registry, Álvarez Acosta L, et al. Spanish catheter ablation registry. 23rd official report of the Heart Rhythm Association of the Spanish Society of Cardiology (2023). Rev Esp Cardiol (Engl Ed). 2024;77(12):1026-1036. doi:10.1016/j.rec.2024.07.014 · PMID 39313188G3
  9. Beneyto M, Chaumont C, Yokoyama M, Raczka F, Thomas O, Marimpouy N, et al. Characteristics of Recurrent Atrial Arrhythmias and Lesion Assessment Late After Pulsed Field Ablation of Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2026;doi: 10.1161/CIRCEP.125.014506. doi:10.1161/CIRCEP.125.014506 · PMID 42755708C4
  10. Boersma LVA, Natale A, Haines D, DeLurgio D, Sood N, Marchlinski F, et al. Prevalence, timing, and impact of early recurrence of atrial tachyarrhythmias after pulsed field ablation: A secondary analysis of the PULSED AF trial. Heart Rhythm. 2025;22(4):884-890. doi:10.1016/j.hrthm.2024.06.036 · PMID 38925335C1C5
  11. Boersma LVA, Széplaki G, Dello Russo A, García-Bolao I, Efremidis M, Szegedi N, et al. Real-world experience with the pentaspline pulsed field ablation system: one-year outcomes of the FARADISE registry. Europace. 2025;27(9). doi:10.1093/europace/euaf182 · PMID 40888735C5G3
  12. Boriani G, Molon G, Nardi S, Mitacchione G, Ricciardi D, Chieffo E, et al. Single-shot ablation for AF: Real-world procedural and one-year outcomes with the newly adopted PulseSelect PFA compared with cryoballoon from the 1STOP project. J Interv Card Electrophysiol. 2026;doi: 10.1007/s10840-026-02392-w. doi:10.1007/s10840-026-02392-w · PMID 42400724G3
  13. Brešković T, Lisica L, Jurišić Z, Petrović D, Sikirić I, Metličić V, et al. Ablation of accessory pathways in different anatomic locations using focal pulsed field ablation. Heart Rhythm. 2024;21(8):1211-1217. doi:10.1016/j.hrthm.2024.03.030 · PMID 38499129G5
  14. Cano-Valls A, Martinez Monblan MA, Carro-Fernández E, Niebla M, Domingo R, Hevia-Puyo S, et al. NURSE-Led Care in Patients Undergoing Catheter Ablation for Atrial Fibrillation: The NURSECAT-AF Randomized Trial. Circ Arrhythm Electrophysiol. 2026;19(3):e014149. doi:10.1161/CIRCEP.125.014149 · PMID 41744095D4
  15. CanoValls A, Carro Fernández E, Guasch Casany E. Unplanned contacts managed by an advanced nurse practitioner after atrial fibrillation ablation. Enferm Clin (Engl Ed). 2026;doi: 10.1016/j.enfcle.2026.502511. doi:10.1016/j.enfcle.2026.502511 · PMID 42880635D4
  16. Castrejón-Castrejón S, Heeger CH, Veltmann C, Schaack D, Nies M, Gunawardene M, et al. Stroke and systemic embolism following atrial fibrillation ablation: the EMBOL-AF Global Registry. Eur Heart J. 2026;47(36):5155-5168. doi:10.1093/eurheartj/ehag217 · PMID 41914181C1G3I1
  17. Chaumont C, Laredo M, Thomas O, Maury P, Massoulié G, Defaye P, et al. Countrywide introduction of pulsed field ablation for the treatment of atrial fibrillation: Acute results from the FRANCE-PFA registry. Heart Rhythm O2. 2025;6(7):911-919. doi:10.1016/j.hroo.2025.04.005 · PMID 40734736C4G3
  18. Compagnucci P, Finori L, Casella M, Gasperetti A, Huang HD, Valeri Y, et al. Ventricular pulsed field ablation from bench to bedside: preclinical and clinical evidence from a systematic review and meta-analysis. Europace. 2026;28(9). doi:10.1093/europace/euag221 · PMID 42615921G5
  19. D'Elia NW, Voskoboinik A, Kistler BS, Baker EK, Sugumar H, Segan L, et al. Pulmonary Vein Reconnection Characteristics After Index Pulsed Field vs Radiofrequency Ablation for Atrial Fibrillation. JACC Clin Electrophysiol. 2026;pii: S2405-500X(26)00548-7. doi: 10.1016/j.jacep.2026.06.003. doi:10.1016/j.jacep.2026.06.003 · PMID 42461200C4
  20. Dasa O, Younis A, Higuchi K, Sroubek J, Lee JZ, Chung R, et al. Early U.S. Experience With Catheter Ablation of Ventricular Arrhythmias With a Dual-Energy Lattice-Tip Catheter: Insights From the CLEAR-VT Registry. JACC Clin Electrophysiol. 2026;12(8):1846-1862. doi:10.1016/j.jacep.2026.03.002 · PMID 42043359G5
  21. Dashwood A, Ha FJ, Healy S, Puchalski R, Cheng SH, Tian B, et al. Vascular Closure Device Following Pulsed Field Ablation for Atrial Fibrillation: A Randomized Controlled Trial. Pacing Clin Electrophysiol. 2025;48(11):1294-1300. doi:10.1111/pace.70051 · PMID 40985473D4
  22. De Potter T, Scherr D, Pürerfellner H, Račkauskas G, Hansen J, Vijgen J, et al. Dual energy for pulmonary vein isolation using focal ablation technology integrated with a three-dimensional mapping system: SmartfIRE 12-month results. Europace. 2025;27(9). doi:10.1093/europace/euaf174 · PMID 40796332C3
  23. De Potter TJR, Valeriano C, Akerstrom F, Cassese S, Finlay M, Gupta D, et al. Vascular access and closure management for electrophysiological interventions in 2025: a Clinical Consensus Statement of the European Heart Rhythm Association and the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the ESC Working Group on Cardiovascular Surgery. Europace. 2025;27(10). doi:10.1093/europace/euaf115 · PMID 41118456C6
  24. Del Monte A, Bisignani A, Della Rocca DG, Schillaci V, Monaco C, Bergonti M, et al. Pulsed field ablation of atrial arrhythmias in patients with cardiac implantable electronic devices: a multicenter evaluation of electrical integrity and device safety. J Interv Card Electrophysiol. 2026;doi: 10.1007/s10840-026-02426-3. doi:10.1007/s10840-026-02426-3 · PMID 42671686C1C4
  25. Dello Russo A, Valeri Y, Ciconte G, Schiavone M, Compagnucci P, Poggi S, et al. Multicentre experience with the variable-loop circular catheter pulsed-field ablation system for atrial fibrillation ablation. Europace. 2026;28(9). doi:10.1093/europace/euag265 · PMID 42746810G3
  26. Desteghe L, Lee G, Antoniou S, Merino JL, Neubeck L, Ross C, et al. A multidisciplinary team approach in the 2024 ESC guidelines for the management of patients with Atrial Fibrillation-what is the role of nurses and allied professionals? A Clinical Consensus Statement of the Association of Cardiovascular Nursing and Allied Professions (ACNAP) and the European Heart Rhythm Association (EHRA) of the ESC. Eur J Cardiovasc Nurs. 2025;24(6):828-840. doi:10.1093/eurjcn/zvaf083 · PMID 40326781D4
  27. Doty B, Mraiyan M, Nair G, Khan M, Gabrah K, Nair DG. Feasibility, procedural efficiency, and early imaging outcomes of concomitant pulsed field ablation and left atrial appendage closure: a prospective single-centre study. Europace. 2026;28(2). doi:10.1093/europace/euag017 · PMID 41643194C4
  28. Duytschaever M, De Potter T, Grimaldi M, Anic A, Vijgen J, Neuzil P, et al. Paroxysmal Atrial Fibrillation Ablation Using a Novel Variable-Loop Biphasic Pulsed Field Ablation Catheter Integrated With a 3-Dimensional Mapping System: 1-Year Outcomes of the Multicenter inspIRE Study. Circ Arrhythm Electrophysiol. 2023;16(3):e011780. doi:10.1161/CIRCEP.122.011780 · PMID 36735937G2
  29. Ekanem E, Neuzil P, Reichlin T, Kautzner J, van der Voort P, Jais P, et al. Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study. Nat Med. 2024;30(7):2020-2029. doi:10.1038/s41591-024-03114-3 · PMID 38977913G3I1
  30. Espinosa T, Farrus A, Venturas M, Cano A, Vazquez-Calvo S, Pujol-Lopez M, et al. Same-day discharge after atrial fibrillation ablation under a nurse-coordinated standardized protocol. Europace. 2024;26(4). doi:10.1093/europace/euae083 · PMID 38571291D4
  31. García-Bolao I, Szegedi N, Vijgen J, Széplaki G, Dello Russo A, Efremidis M, et al. Pulsed Field Ablation as First-Line Therapy for the Treatment of Atrial Fibrillation: a FARADISE Sub-Analysis. Europace. 2026;pii: euag275. doi: 10.1093/europace/euag275. doi:10.1093/europace/euag275 · PMID 42872380G3
  32. Gerstenfeld EP, Schmidt B, Natale A, Nair D, Saliba W, Verma A, et al. Pulsed Field Ablation vs Standard Radiofrequency Ablation for Typical Atrial Flutter: ADVANTAGE AF Trial Substudy. J Am Coll Cardiol. 2026;87(14):1764-1778. doi:10.1016/j.jacc.2025.12.081 · PMID 41653174C4G5
  33. Gianni C, Al-Ahmad A, Elchouemi M, La Fazia VM, Mohanty S, Allison JD, et al. Pulsed Field Ablation-Related Hemolysis: Comparison Between Technologies. Circ Arrhythm Electrophysiol. 2025;18(12):e014021. doi:10.1161/CIRCEP.125.014021 · PMID 41328578C3
  34. Goto K, Miyazaki S, Nakamura K, Nitta J, Murakami M, Hasegawa K, et al. A randomized controlled trial of two pulsed field ablation systems for paroxysmal atrial fibrillation: the DUAL-PULSE trial rationale and design. J Interv Card Electrophysiol. 2025;68(9):1801-1807. doi:10.1007/s10840-025-02137-1 · PMID 41042294C3
  35. Gunawardene MA, Schmidt B, Peichl P, Nair D, Sanders P, Abbas M, et al. Life-Threatening Delayed Myocardial Ischemia and Malignant Arrhythmias Occurring After Pulsed Field Ablation of Atrial Fibrillation. Circulation. 2026;153(10):789-793. doi:10.1161/CIRCULATIONAHA.125.077983 · PMID 41446933C1I1
  36. Hartl S, Reinsch N, Füting A, Neven K. TWOSOME trial: Randomized comparison of single-shot vs single-tip pulsed field ablation for pulmonary vein isolation. Heart Rhythm. 2026;pii: S1547-5271(26)02338-6. doi: 10.1016/j.hrthm.2026.04.049. doi:10.1016/j.hrthm.2026.04.049 · PMID 42092568C3G2
  37. Heeger CH, Roten L, Della Rocca D, Velagić V, Gupta D, De Potter T, et al. COnCOmitaNt pulsed field ablation-based pUlmonary vein isolation and lefT atrial appendage closure: the COCONUT study. Europace. 2026;28(9). doi:10.1093/europace/euag198 · PMID 42713747C1C4
  38. Hussein AA, Rackauskas G, Sundaram S, Piccini JP, Roithinger FX, Tung P, et al. Safety and Effectiveness of a Novel Dual-Energy Radiofrequency/Pulsed Field Ablation Catheter: 12 Month Results of the FlexPulse Study. Europace. 2026;pii: euag238. doi: 10.1093/europace/euag238. doi:10.1093/europace/euag238 · PMID 42667242C5G2
  39. Inoue K, Kanaoka K, Ueda Y, Abe H, Ikeoka K, Mishima T, et al. Periprocedural Mortality Risk After Elective Atrial Fibrillation Ablation in Japan. JAMA Netw Open. 2026;9(8):e2634516. doi:10.1001/jamanetworkopen.2026.34516 · PMID 42667122G3
  40. Jais P, Neuzil P, Scherr D, Frison E, Knecht S, Boveda S, et al. Pulsed field vs radiofrequency ablation for paroxysmal atrial fibrillation: the BEAT PAROX-AF trial. Eur Heart J. 2026;47(13):1527-1537. doi:10.1093/eurheartj/ehaf1115 · PMID 41568658G2I2
  41. Joglar JA, Chung MK, Armbruster AL, Benjamin EJ, Chyou JY, Cronin EM, et al. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2024;149(1):e1-e156. doi:10.1161/CIR.0000000000001193 · PMID 38033089G1
  42. Karakasis P, Fragakis N, Tzeis S, Frontera A, Siontis KC, Antoniadis AP, et al. Comparative efficacy and safety of catheter ablation energy modalities for atrial fibrillation: A network meta-analysis of randomized trials. Heart Rhythm. 2026;pii: S1547-5271(26)02405-7. doi: 10.1016/j.hrthm.2026.05.038. doi:10.1016/j.hrthm.2026.05.038 · PMID 42203053G2I2
  43. Kawamura I, Miyazaki S, Kato R, Takahashi K, Negishi M, Honda M, et al. Comparison of hemolysis with different pulsed field ablation systems. Heart Rhythm. 2026;23(2):388-395. doi:10.1016/j.hrthm.2025.05.072 · PMID 40472952C3
  44. Keelani A, Tavkhelidze S, Lisica L, Ruwald MH, Chaldoupi SM, Alothman O, et al. Safety and Midterm Outcome of Focal Pulsed Field Ablation for Outflow Tract Premature Ventricular Contractions: A Prospective Multicenter Study. JACC Clin Electrophysiol. 2026;12(9):2120-2132. doi:10.1016/j.jacep.2026.03.032 · PMID 42101393G5
  45. Kueffer T, Bordignon S, Neven K, Blaauw Y, Hansen J, Adelino R, et al. Durability of Pulmonary Vein Isolation Using Pulsed-Field Ablation: Results From the Multicenter EU-PORIA Registry. JACC Clin Electrophysiol. 2024;10(4):698-708. doi:10.1016/j.jacep.2023.11.026 · PMID 38340118C1C4
  46. Køber L, Adamo M, Ruwald AC, Tomasoni D, Anderson LJ, Andersson C, et al. 2026 ESC Guidelines for the management of heart failure. Eur Heart J. 2026;47(38):5346-5457. doi:10.1093/eurheartj/ehag100 · PMID 42661420G1
  47. Kühne M, Badertscher P, Andrade JG, Anic A, Chun J, Dello Russo A, et al. Pulsed field ablation for the interventional treatment of atrial fibrillation: a scientific statement of the European Heart Rhythm Association of the European Society of Cardiology, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society. Europace. 2026;28(6). doi:10.1093/europace/euag080 · PMID 41968953C5C7G1G5
  48. Latini AC, Penna M, Saglietto A, Landra F, Chiarito M, Villaschi A, et al. Pulsed field ablation vs. thermal ablation for pulmonary vein isolation: a network meta-analysis of randomized controlled trials. Europace. 2026;28(6). doi:10.1093/europace/euag112 · PMID 42116662G2
  49. Li F, Gong A, Hu H, Cui K, Yang Q, Pu X, et al. Pulsed Field Ablation of Paroxysmal Supraventricular Tachycardia: A Prospective Multicenter Single-Arm Study in China. Circ Arrhythm Electrophysiol. 2024;17(12):e013206. doi:10.1161/CIRCEP.124.013206 · PMID 39611270G5
  50. Li F, Hu X, Li Z, Li W, Ren B, Wang Y, et al. Pulsed electric field and radiofrequency ablation for paroxysmal supraventricular tachycardia: a propensity score-matched comparison (PFA-SVT study). Clin Res Cardiol. 2026;doi: 10.1007/s00392-026-02901-x. doi:10.1007/s00392-026-02901-x · PMID 41925740G5
  51. Lin W, Chu H, Wang C, Chang D, Yin X, Wang Y, et al. Pulsed Field Ablation Using a Novel Biphasic Catheter vs Thermal Ablation for Paroxysmal Atrial Fibrillation: InsightPFA Trial. J Am Coll Cardiol. 2025;86(23):2314-2326. doi:10.1016/j.jacc.2025.09.1593 · PMID 41338842G2
  52. Lorente-Ros M, Kerley R, Keane D, Hadadi C, Shah M, Thomaides A, et al. Pulsed field ablation for pulmonary vein isolation with or without posterior wall ablation in patients with persistent atrial fibrillation: a multicenter study. J Interv Card Electrophysiol. 2026;doi: 10.1007/s10840-026-02402-x. doi:10.1007/s10840-026-02402-x · PMID 42440226G5
  53. Malyar CV, Kovacs B, Mahmoodi BK, Haeberlin A, Reichlin T, Yap SC. Permanent damage to implantable cardioverter-defibrillators during left-sided septal ventricular tachycardia ablation using a lattice-tip catheter: A case series. Heart Rhythm. 2026;23(5):1035-1039. doi:10.1016/j.hrthm.2026.01.028 · PMID 41581847G5
  54. Malyshev Y, Neuzil P, Petru J, Funasako M, Hala P, Kopriva K, et al. Nitroglycerin to Ameliorate Coronary Artery Spasm During Focal Pulsed-Field Ablation for Atrial Fibrillation. JACC Clin Electrophysiol. 2024;10(5):885-896. doi:10.1016/j.jacep.2023.12.015 · PMID 38385916C1C4I1
  55. Manninger M, Scherr D, Bulava A, Kalman J, Sanders P, Della Bella P, et al. Safety and effectiveness of the TactiFlex duo system: 6-month results of the FOCALFLEX study. Europace. 2026;28(5). doi:10.1093/europace/euag108 · PMID 42097576G2
  56. Matsumoto K, van Bragt KA, Kueffer FJ, Mburu W, Tarakji KG. Indirect treatment comparison of two pulsed field ablation systems for the treatment of persistent atrial fibrillation. J Interv Card Electrophysiol. 2026;69(3):355-363. doi:10.1007/s10840-025-02124-6 · PMID 40928625C3
  57. Mehta K, Arshad H, Arshad I, Abbas M, Ahuja A, Agrawal P, et al. Efficacy, safety, and procedural outcomes of pulsed field ablation for cavotricuspid isthmus-dependent atrial flutter: a systematic review and single-arm meta-analysis. J Interv Card Electrophysiol. 2026;doi: 10.1007/s10840-026-02362-2. doi:10.1007/s10840-026-02362-2 · PMID 42213396G5
  58. Mené R, Sousonis V, Schmidt B, Bordignon S, Neven K, Reichlin T, et al. Safety and efficacy of pulsed-field ablation for atrial fibrillation in the elderly: A EU-PORIA sub-analysis. Int J Cardiol. 2024;417:132522. doi:10.1016/j.ijcard.2024.132522 · PMID 39245073C1C4
  59. Musikantow DR, Reddy VY, Skalsky I, Shaburishvili T, van Zyl M, O'Brien B, et al. Targeted ablation of epicardial ganglionated plexi during cardiac surgery with pulsed field electroporation (NEURAL AF). J Interv Card Electrophysiol. 2025;68(2):467-474. doi:10.1007/s10840-023-01615-8 · PMID 37561246G5
  60. Nakasone K, Duytschaever M, Almorad A, Magnocavallo M, Vetta G, Pannone L, et al. Incidence, Mechanistic Insights, and Ablation of Atrial Tachycardia Occurring After Pulsed Field Ablation for Atrial Fibrillation: Results From a Large International Registry. JACC Clin Electrophysiol. 2026;pii: S2405-500X(26)00473-1. doi: 10.1016/j.jacep.2026.05.017. doi:10.1016/j.jacep.2026.05.017 · PMID 42319332C4
  61. Navarro-Manchón J, Izquierdo de Francisco MT, Cano Pérez Ó, Chorro Gascó FJ, Martínez-Dolz L, Osca Asensi J. Insights into the optimal blanking period after pulmonary vein isolation with radiofrequency or pulsed-field ablation. Rev Esp Cardiol (Engl Ed). 2026;79(4):387-389. doi:10.1016/j.rec.2025.08.008 · PMID 41033488G3
  62. Okumura Y, Tokuda M, Nagashima K, Watanabe R, Wakamatsu Y, Hirata S, et al. PERSIST-PWI trial: Rationale and design of a multicenter randomized controlled trial comparing pulmonary vein isolation alone with pulmonary vein isolation plus posterior wall isolation using pulsed field ablation in patients with persistent atrial fibrillation. Heart Rhythm O2. 2026;7(6):1182-1189. doi:10.1016/j.hroo.2026.03.013 · PMID 42369805G5
  63. Osmancik P, Neuzil P, Hozmanova J, Petru J, Herman D, Kralovec S, et al. Pulsed Field Ablation Versus Sham to Treat Atrial Fibrillation: The PFA-SHAM Randomized Clinical Trial. Circulation. 2026;153(25):1984-1998. doi:10.1161/CIRCULATIONAHA.126.079484 · PMID 42186803G2I2
  64. Palmisano P, Bonanno S, Campisi G, Palamà Z, Collantoni M, Rapisarda G, et al. Predictive value of early recurrence after atrial fibrillation ablation: A propensity-matched comparison between pulsed field ablation and radiofrequency ablation. Heart Rhythm. 2026;23(10):e2449-e2455. doi:10.1016/j.hrthm.2026.04.006 · PMID 41997389G3
  65. Reddy VY, Gerstenfeld EP, Natale A, Whang W, Cuoco FA, Patel C, et al. Pulsed Field or Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation. N Engl J Med. 2023;389(18):1660-1671. doi:10.1056/NEJMoa2307291 · PMID 37634148G2
  66. Reddy VY, Calkins H, Mansour M, Wazni O, Di Biase L, Bahu M, et al. Pulsed Field Ablation to Treat Paroxysmal Atrial Fibrillation: Safety and Effectiveness in the AdmIRE Pivotal Trial. Circulation. 2024;150(15):1174-1186. doi:10.1161/CIRCULATIONAHA.124.070333 · PMID 39258362G2
  67. Reddy VY, Gerstenfeld EP, Schmidt B, Andrade JG, Nair D, Natale A, et al. Pulsed Field Ablation of Persistent Atrial Fibrillation With Continuous Electrocardiographic Monitoring Follow-Up: ADVANTAGE AF Phase 2. Circulation. 2025;152(1):27-40. doi:10.1161/CIRCULATIONAHA.125.074485 · PMID 40273320C7G2
  68. Reddy VY, Gerstenfeld EP, Schmidt B, Nair D, Natale A, Saliba W, et al. Pulsed Field Ablation for Persistent Atrial Fibrillation: 1-Year Results of ADVANTAGE AF. J Am Coll Cardiol. 2025;85(17):1664-1678. doi:10.1016/j.jacc.2025.03.515 · PMID 40306839G2
  69. Reddy VY, Koruth JS, Peichl P, Petru J, Funasako M, Skoda J, et al. High-Voltage Focal Pulsed Field Ablation to Treat Scar-Related Ventricular Tachycardia: The First-in-Human VCAS Trial. Circulation. 2025;152(24):1691-1704. doi:10.1161/CIRCULATIONAHA.125.077025 · PMID 41071961G5
  70. Reddy VY, Gerstenfeld EP, Mountantonakis SE, Patel C, Ellenbogen KA, Harding JD, et al. Pulsed field ablation versus conventional thermal ablation for paroxysmal atrial fibrillation: 4-year outcomes in the ADVENT-LTO study. Nat Med. 2026;32(4):1444-1453. doi:10.1038/s41591-026-04246-4 · PMID 41652117G2
  71. Reichlin T, Kueffer T, Badertscher P, Jüni P, Knecht S, Thalmann G, et al. Pulsed Field or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation. N Engl J Med. 2025;392(15):1497-1507. doi:10.1056/NEJMoa2502280 · PMID 40162734G2I2
  72. Reis Santos R, Bello R, Santos PG, Matos D, Rodrigues G, Carmo J, et al. Safety and effectiveness of pulsed field ablation for pulmonary vein isolation in atrial fibrillation patients: One-year single center experience. Rev Port Cardiol. 2025;44(5):269-275. doi:10.1016/j.repc.2024.09.006 · PMID 39870306G3
  73. Ribatti V, Dello Russo A, Riva S, Malacrida M, Bianchi S, Solimene F, et al. De Novo Pulmonary Vein Isolation by Means of Pulsed Field Versus Conventional Thermal Ablation of Paroxysmal Atrial Fibrillation in Women: Safety, Efficiency, and Efficacy. J Am Heart Assoc. 2026;15(5):e041873. doi:10.1161/JAHA.125.041873 · PMID 41676924C1C4
  74. Rodriguez-Riascos JF, Somappa A, Estrada-Vargas CA, Navale D, Vemulapalli HS, Kim JY, et al. Safety and Efficacy of Pulsed Field Ablation for Atrial Fibrillation in Patients With Chronic Kidney Disease. Heart Rhythm. 2026;pii: S1547-5271(26)02857-2. doi: 10.1016/j.hrthm.2026.09.053. doi:10.1016/j.hrthm.2026.09.053 · PMID 42838316C1C4
  75. Rodríguez Muñoz D, López-Alacid I, Cobarro Gálvez L, Rajjoub Al-Mahdi EA, Marco Del Castillo Á, Ramos Jiménez J, et al. Pulmonary vein isolation durability in a randomized trial comparing fluoroscopy-only vs. electroanatomic mapping strategies for pulmonary vein isolation with balloon-in-basket pulsed-field ablation. Europace. 2026;28(9). doi:10.1093/europace/euag244 · PMID 42689939C3
  76. Roten L, Maurhofer J, Krisai P, Breitenstein A, Koepfli P, Saguner AM, et al. Pulmonary Vein Isolation Using Pulsed Field Ablation With vs Without Posterior Wall Isolation in Patients With Symptomatic Persistent Atrial Fibrillation: The PIFPAF-PFA Randomized Clinical Trial. JAMA. 2026;doi: 10.1001/jama.2026.17598. doi:10.1001/jama.2026.17598 · PMID 42667231C1C5G2G5I2
  77. Sacher F, Sarkozy A, Pürerfellner H, Steyer A, Lyne J, Coquard C, et al. Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR). Europace. 2025;27(9). doi:10.1093/europace/euaf139 · PMID 40601816G5
  78. Schaack D, Chun KJ, Neven K, Metzner A, Heeger C, Wakili R, et al. Ultrasound-guided vs conventional venous puncture for atrial fibrillation ablation: the ULYSSES trial. Eur Heart J. 2026;47(36):5142-5151. doi:10.1093/eurheartj/ehag291 · PMID 41979041C6
  79. Scherr D, Bessière F, Kronborg MB, Sebag F, Sohns C, Pappone C, et al. Effectiveness of AF pulsed field ablation with a variable-loop circular catheter: 12-month VARIPURE results. Europace. 2026;28(6). doi:10.1093/europace/euag082 · PMID 41968105G3
  80. Scherr D, Frausing MHJP, Maciejewski C, Barisone M, Boriani G, Breitenstein A, et al. Same-day discharge after electrophysiological and cardiac implantable electronic device procedures: a clinical consensus statement of the European Heart Rhythm Association (EHRA) and the Association of Cardiovascular Nursing & Allied Professions (ACNAP) of the ESC. Europace. 2026;28(4). doi:10.1093/europace/euag065 · PMID 41973847C5D4
  81. Schiavone M, La Fazia VM, Fassini G, Gasperetti A, Mohanty S, Bianchini L, et al. Pulsed field ablation with a pentaspline catheter and concomitant left atrial appendage closure for long-standing persistent atrial fibrillation: Comparison with a radiofrequency cohort. Heart Rhythm. 2026;23(10):e2415-e2424. doi:10.1016/j.hrthm.2026.04.018 · PMID 42002011C4
  82. Schiavone M, Solimene F, Dello Russo A, Bianchi S, Iacopino S, Malacrida M, et al. Pulsed field ablation for atrial fibrillation in patients with heart failure: insight from the ATHENA registrys. Europace. 2026;28(4). doi:10.1093/europace/euag049 · PMID 41910215C1C4C5G3
  83. Schmidt B, Bordignon S, Neven K, Reichlin T, Blaauw Y, Hansen J, et al. EUropean real-world outcomes with Pulsed field ablatiOn in patients with symptomatic atRIAl fibrillation: lessons from the multi-centre EU-PORIA registry. Europace. 2023;25(7). doi:10.1093/europace/euad185 · PMID 37379528G3
  84. Shen C, Bai R, Jia Z, Feng M, Yu Y, Du X, et al. Unexpected transient atrioventricular block and slow junctional rhythm using pulsed field ablation for slow pathway modification: Excited or cautious for ablators. Heart Rhythm. 2025;22(7):1682-1692. doi:10.1016/j.hrthm.2024.09.023 · PMID 39304002G5
  85. Sroubek J, Baranowski B, Bhargava M, Callahan TD, Chung MK, Chung R, et al. Design and rationale of the pulse field ablation for postinfarction ventricular tachycardia: The ASCEND-VT pilot study. Heart Rhythm O2. 2026;7(8):1564-1572. doi:10.1016/j.hroo.2026.04.008 · PMID 42666642G5
  86. Sánchez-Gómez JM, Ortiz-Fernández Á, Soler-Martínez J, Gabaldón-Pérez A, Iraola-Viana D, Martínez-Brotons Á, et al. Incidence of brain lesions following pulsed field ablation for atrial fibrillation. Heart Rhythm. 2026;23(1):8-15. doi:10.1016/j.hrthm.2025.02.020 · PMID 40736426G3
  87. Tilz RR, Chierchia GB, Gunawardene M, Sanders P, Haqqani H, Kalman J, et al. Safety and effectiveness of the first balloon-in-basket pulsed field ablation system for the treatment of atrial fibrillation: VOLT CE Mark Study 6-month results. Europace. 2025;27(4). doi:10.1093/europace/euaf072 · PMID 40163671G2
  88. Turagam MK, Neuzil P, Schmidt B, Reichlin T, Neven K, Metzner A, et al. Safety and Effectiveness of Pulsed Field Ablation to Treat Atrial Fibrillation: One-Year Outcomes From the MANIFEST-PF Registry. Circulation. 2023;148(1):35-46. doi:10.1161/CIRCULATIONAHA.123.064959 · PMID 37199171G3
  89. Turagam MK, Neuzil P, Schmidt B, Reichlin T, Neven K, Metzner A, et al. Safety and Effectiveness of Pulsed Field Ablation for Atrial Fibrillation in Patients With Heart Failure. JACC Clin Electrophysiol. 2024;pii: S2405-500X(24)00351-7. doi: 10.1016/j.jacep.2024.05.002. doi:10.1016/j.jacep.2024.05.002 · PMID 38864809C4G3
  90. Turagam MK, Aryana A, Day JD, Dukkipati SR, Hounshell T, Nair D, et al. Multicenter Study on the Safety of Pulsed Field Ablation in Over 40,000 Patients: MANIFEST-US. J Am Coll Cardiol. 2026;87(2):172-193. doi:10.1016/j.jacc.2025.10.051 · PMID 41389071C5G3I1
  91. Tzeis S, Gerstenfeld EP, Kalman J, Saad EB, Sepehri Shamloo A, Andrade JG, et al. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace. 2024;26(4). doi:10.1093/europace/euae043 · PMID 38587017C5C7G1
  92. Urbanek P, Bodalski R, Orczykowski M, Kowalik I, Głowniak A, Ponikowski P, et al. Pulsed Field Ablation Is Associated With Favorable Outcomes After Atrial Fibrillation Ablation: Insights From the Polish National Ablation Registry (POL-AR). J Cardiovasc Electrophysiol. 2026;37(10):2385-2392. doi:10.1111/jce.70514 · PMID 42801701G3
  93. van der Graaf M, Abeln BGS, Balt JC, Mittal S, Knight BP, Gunawardene MA, et al. Comparison of Two Pulsed Field Ablation Systems for Atrial Fibrillation: One-Year Outcomes From a Multicenter Registry. J Cardiovasc Electrophysiol. 2026;37(7):1522-1532. doi:10.1111/jce.70375 · PMID 42188995C3
  94. Van Gelder IC, Rienstra M, Bunting KV, Casado-Arroyo R, Caso V, Crijns HJGM, et al. 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2024;45(36):3314-3414. doi:10.1093/eurheartj/ehae176 · PMID 39210723G1
  95. Vanharen Y, Abugattas de Torres JP, Adriaenssens B, Convens C, Schwagten B, Tijskens M, et al. Nurse-led care after ablation of atrial fibrillation: a randomized controlled trial. Eur J Prev Cardiol. 2023;30(15):1599-1607. doi:10.1093/eurjpc/zwad117 · PMID 37067048D4
  96. Verma A, Haines DE, Boersma LV, Sood N, Natale A, Marchlinski FE, et al. Pulsed Field Ablation for the Treatment of Atrial Fibrillation: PULSED AF Pivotal Trial. Circulation. 2023;147(19):1422-1432. doi:10.1161/CIRCULATIONAHA.123.063988 · PMID 36877118G2
  97. Verma A, Hocini M, Andrade J, Gerstenfeld E, Kapa S, Lakkireddy D, et al. 2026 HRS/EHRA scientific statement on pulsed field ablation for cardiac arrhythmias. Heart Rhythm. 2026;23(9):e2195-e2234. doi:10.1016/j.hrthm.2026.02.006 · PMID 41690439C5C6D4G1G5
  98. Verma A, Lo M, Woods CE, Hussein AA, Gambhir A, Sundaram S, et al. Balloon-in-Basket Pulsed Field Ablation for Pulmonary Vein Isolation: 1-Year Outcomes of the VOLT-AF IDE Study. JACC Clin Electrophysiol. 2026;12(6):1287-1299. doi:10.1016/j.jacep.2026.01.006 · PMID 41649432G2
  99. Wachter R, Haag P, Uhe T, Bacak M, Petroff D, Forkmann M, et al. Catheter ablation for symptomatic atrial fibrillation (PVI-SHAM-AF): a randomised, double-blind, sham-controlled, multicentre trial. Lancet. 2026;408(10559):999-1009. doi:10.1016/S0140-6736(26)01558-8 · PMID 42669307G2
  100. Wazni OM, Chun KJ, Amin A, Anic A, Ajijola OA, Gibson DN, et al. A randomized controlled trial of pulsed field ablation vs antiarrhythmic therapy as a first-line treatment for persistent atrial fibrillation: The AVANT GUARD trial rationale and design. Heart Rhythm O2. 2026;7(3):561-574. doi:10.1016/j.hroo.2025.12.011 · PMID 41908201G2
  101. Wazni OM, Chun KRJ, Nair DG, Anic A, Duytschaever M, Chrispin J, et al. Pulsed Field Ablation as Initial Therapy for Persistent Atrial Fibrillation. N Engl J Med. 2026;394(24):2407-2418. doi:10.1056/NEJMoa2600929 · PMID 42041224C1C5G2G5I2
  102. Wenzel JP, Abdessadok R, Eitel C, Vogler J, Hatahet S, Nikorowitsch J, et al. Catheter Design Matters: Hemolysis and Renal Function after Pulsed Field Ablation with Balloon-in-Basket vs. Pentaspline Systems. J Interv Card Electrophysiol. 2026;69(6):1169-1179. doi:10.1007/s10840-025-02152-2 · PMID 41066058C3
  103. Wong EA, Zei PC, Hincapie D, Dai C, Koplan BA, Ruble S, et al. Early Safety Profile Using Pulsed Field Ablation: Prospective Multicenter DISRUPT-AF Study. JACC Clin Electrophysiol. 2026;pii: S2405-500X(26)00454-8. doi: 10.1016/j.jacep.2026.04.032. doi:10.1016/j.jacep.2026.04.032 · PMID 42360264G3
  104. Yassin AS, Mahmoodi BK, Mulder BA, Malyar CV, Rienstra M, Yap SC, et al. Incremental value of electroanatomical mapping during pentaspline pulsed field pulmonary vein isolation: the MAP-PFA pilot randomized trial. Europace. 2026;28(9). doi:10.1093/europace/euag222 · PMID 42615914C3

Otros documentos con DOI (1)

  1. Rubio-Campal JM, García BC, Amador PB, Rodríguez-Entem F, Cuervo DC. Registro español de ablación con catéter. XXV informe oficial de la Asociación del Ritmo Cardiaco de la Sociedad Española de Cardiología (2025). Revista Española de Cardiología. 2026. doi:10.1016/j.recesp.2026.07.011E3

Ensayos en marcha (ClinicalTrials.gov) (6)

  1. CRAAFT-HF. Ablación con crioablación, radiofrecuencia o campo pulsado frente al tratamiento médico en la FA con insuficiencia cardiaca: muerte por cualquier causa u hospitalización cardiovascular urgente, con al menos 2 años de seguimiento. ClinicalTrials.gov, NCT06505798; 1.200 pacientes · aleatorizado; reclutando · resultados primarios previstos: diciembre de 2031 · promotor: University College London. Consultado el 19/10/2026. NCT06505798I2
  2. DOPPIO. Más aplicaciones con el catéter pentaspline (2 en forma de oliva, 4 de cesta y 6 de flor) frente a la pauta estándar (4 de cesta y 4 de flor) para un aislamiento más duradero: libres de FA a 18 meses, tras un periodo inicial de 2 meses. ClinicalTrials.gov, NCT07021313; 378 pacientes · aleatorizado; activo, sin reclutar · resultados primarios previstos: junio de 2027 · promotor: R&D Cardiologie. Consultado el 19/10/2026. NCT07021313I2
  3. HYDRATE-PFA. Hidratación con suero salino al 0,9% (2 mL/kg/h desde la entrada en la sala hasta 12 horas después) frente a no hidratar de rutina, para prevenir la lesión renal aguda (criterios KDIGO) tras el campo pulsado; abierto, de un centro. ClinicalTrials.gov, NCT07490808; 290 pacientes · aleatorizado; activo, sin reclutar · resultados primarios previstos: julio de 2026, fecha ya alcanzada según el registro, que aún no publica resultados · promotor: Beijing Anzhen Hospital. Consultado el 19/10/2026. NCT07490808I2
  4. PVI-MODE. Los sistemas de aislamiento de las venas pulmonares que se usan en la práctica, comparados por periodos (aleatorización por grupos): cuatro de campo pulsado y la crioablación; FA o flúter a los 6 y a los 12 meses. ClinicalTrials.gov, NCT07456540; 1.125 pacientes · aleatorizado por grupos; aún sin reclutar · resultados primarios previstos: abril de 2030 · promotor: Rigshospitalet, Copenhague. Consultado el 19/10/2026. NCT07456540I2
  5. PVI-PLUS. Aislamiento de las venas pulmonares solo, frente a añadir la pared posterior y la vena cava superior, con campo pulsado, en la FA persistente, con monitor implantable: libres de FA a 12 meses. ClinicalTrials.gov, NCT07405359; 220 pacientes · aleatorizado; reclutando · resultados primarios previstos: agosto de 2028 · promotor: Edward Gerstenfeld (investigador promotor). Consultado el 19/10/2026. NCT07405359I2
  6. SEDATE-PFA. Sedación consciente (remimazolam, fentanilo y lidocaína) frente a anestesia general en el primer campo pulsado por FA paroxística: hipotensión (sistólica <85 mmHg) o hipoxemia (saturación <85%) mantenidas más de 60 segundos. ClinicalTrials.gov, NCT07541339; 224 pacientes · aleatorizado; aún sin reclutar · resultados primarios previstos: diciembre de 2026 · promotor: Beijing Anzhen Hospital. Consultado el 19/10/2026. NCT07541339I2
La lista se genera sola a partir de lo que citan los módulos (PubMed por PMID, DOI resuelto en PubMed o en CrossRef, CIMA y ClinicalTrials.gov) y se rehace al regenerar el ESPACIO; seis autores y «et al.», como pide el estilo Vancouver.

ESPACIO formativo de CardioTeca.com sobre ablación con campo pulsado. Contenidos elaborados con independencia editorial y dirigidos a profesionales sanitarios. Los fármacos se nombran por su denominación común internacional. Edita y revisa el Comité Editorial de CardioTeca. Última actualización: .

Comité científico · Independencia editorial · Preguntas sobre el ESPACIO