Lo Mejor del ACC 2014 Washington

Lo Mejor del ACC 2014 Washington. Te presentamos una selección de los contenidos más relevantes que no te puedes perder, será como si hubieras estado allí.

Estudios Destacados

• US COREVALVE (TAVI autoexpandible) vs. cirugía convencional en pacientes de alto riesgo »
  Resultados: In patients with severe aortic stenosis who are at increased surgical risk, TAVR with a self-expanding transcatheter aortic-valve bioprosthesis was associated with a significantly higher rate of survival at 1 year than surgical aortic-valve replacement.
  


• Estudio SYMPLICITY HTN-3 o el cambio de mentalidad en denervación renal »
  Resultados: This blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control.
  


• Estudio DESCARTES: Eficacia de Evolocumab en el tratamiento de la hiperlipemia »
  Resultados: At 52 weeks, evolocumab added to diet alone, to low-dose atorvastatin, or to high-dose atorvastatin with or without ezetimibe significantly reduced LDL cholesterol levels in patients with a range of cardiovascular risks.
  


• Estudio AleCardio: Eficacia de Aleglitazar en pacientes diabéticos con Síndrome Coronario Agudo »
  Resultados: Among patients with type 2 diabetes and recent ACS, use of aleglitazar did not reduce the risk of cardiovascular outcomes. These findings do not support the use of aleglitazar in this setting with a goal of reducing cardiovascular risk.
  


• Estudio MADIT-CRT: Mejora de la supervivencia con Resincronización cardiaca en la Insuficiencia Cardiaca NYHA I ó II, seguimiento a 7 años »
  Resultados: Our findings indicate that in patients with mild heart-failure symptoms, left ventricular dysfunction, and left bundle-branch block, early intervention with CRT-D was associated with a significant long-term survival benefit.
  


• Autotransplantation of Bone Marrow Derived Mesenchymal Stromal Cells in Patients with Severe Ischemic Heart Failure: The MSC-HF Trial »
  


• Effect of Inhibition of Lipoprotein-Associated Phospholipase A2 with Darapladib on Ischemic Events in Patients with Chronic Coronary Heart Disease: The STABILITY Trial »
  


• The Low-density Lipoprotein Cholesterol Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy - 2 Trial: A Phase 3, Double-blind, Randomized, Placebo and Ezetimibe Controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Combination With Statin Therapy in Subjects With Primary Hypercholesterolemia and Mixed Dyslipidemia - (LAPLACE-2) »
  


• A Phase 3 Double-blind, Randomized Study to Assess the Safety and Efficacy of Evolocumab (AMG 145) in Hypercholesterolemic Subjects Unable to Tolerate an Effective Dose of Statin - GAUSS-2 »
  


• Efficacy And Safety of Colchicine in Patients with Multiple Recurrences of Pericarditis: Results Of A Multicenter, Double-blind, Placebo-controlled, Randomized Study (CORP-2 Trial) »
  


• The Global SYMPLICITY Registry: Safety and Effectiveness of Renal Artery Denervation In Real World Patients With Uncontrolled Hypertension »
  


• One Year Follow-up of the Melody Transcatheter Pulmonary Valve Multicenter Post Approval Study »
  


• Negative High-Sensitive Troponins in the Emergency Department and Risk of Myocardial Infarction »
  


• PeriOperative ISchemic Evaluation-2 Trial (POISE-2) »
  


• A Large International Trial Assessing the Effects of Clonidine on Major Arterial Events in Patients Having Noncardiac Surgery »
  


• Steroids In caRdiac Surgery Trial (SIRS Trial) »
  


• Metformin in Acute Myocardial Infarction (GIPS-III) »
  


• Effect of Bariatric Surgery vs. Intensive Medical Therapy on Long-term Glycemic Control and Complications of Diabetes: 3-Year STAMPEDE Trial Results »
  


• One Year Outcomes from the STS/ACC Transcatheter Valve Therapy (TVT) Registry »
  


• Two-year Outcome of a Trial Comparing Second Generation Drug-eluting Stents Using Either Biodegradable Polymer or Durable Polymer: The NEXT trial »
  


• How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary Intervention (HEAT-PPCI) »
  


• Bare Metal vs. Zotarolimus-eluting stent in Uncertain Drug-eluting Stent Candidates: A Randomized Controlled Trial (ZEUS) »